Threshold substance concentration (threshold subst.c.) - Dynamic NPU Manual

Threshold substance concentration (threshold subst.c.)

by | Jan 31, 2020 | List of kinds-of-property, Kind-of-quantity

Threshold substance concentration (threshold subst.c.)

Abbreviation

 Threshold subst.c.

Definition in words

Lowest value of substance concentration of component B in system 1 to stimulate a specific reaction

Note 1: “Threshold is a modifier indicating that the kind-of-property is defined as the lowest value of a property eliciting a reaction given by the component and specified by the procedure” (Ref 1)

Note 2: The “specified reaction” must be described somewhere else than in the NPU syntax

Definition by equation

Systematic terms

 Threshold mass concentration of component B in system 1

Result type

 Rational scale
  • Value sets are positive numerical values
  • Algebraic operations are allowed (a=nb; a≠nb)
 Numerical values from 0-∞

Unit

 µmol/L, mmol/L, mol/L etc.

Reference
  1. Blombäck, M., René Dybkær, K. Jørgensen, et al. 2009. Properties and units in the clinical laboratory sciences V. Properties and units in thrombosis and haemostasis (Technical Report). Pure and Applied Chemistry. 69(5): 1043-1080. Retrieved 13 Sep. 2019, from doi:10.1351/pac199769051043
  2. Ferard G, Dybkaer R, Fuentes-Arderiu X. Compendium of Terminology and Nomenclature of Properties in Clinical Laboratory Sciences : Recommendations 2016. 1 ed: Royal Society of Chemistry; 2016. 182 p. Doi:10.1039/9781782622451.

Laboratory field

Examples

Clinical Microbiology

 Example 1
Generic abbreviated
 NPU13569 Syst—Tobramycin; threshold subst.c. = ? µmol/L
Full result NPU13569 System—Tobramycin; threshold substance concentration = 1.4 micromol per liter
Abbreviated result NPU13569 Syst—Tobramycin; threshold subst.c. = 1.4 µmol/L
Written expression The threshold substance concentration of Tobramycin in Mrs. Smith’s system is [1.4] µmol/L.
Equation

 
  1. The NPU code is a context-dependent code (see microbiological structure)
  2. The context-dependent code is attached a list code, in which the system and reaction are specified.

Thrombosis and Haemostasis
Example 2
Generic abbreviated
 NPU01109 Trcs(B)—Aggregation, arachidonate-induced; threshold subst.c.(proc.) = ? µmol/L
Full result NPU01109 Thrombocytes(Blood)—Aggregation, arachidonate-induced; threshold substance concentration(procedure) = 25 micromol per liter
Abbreviated result NPU01109 Trcs(B)—Aggregation, arachidonate-induced; threshold subst.c.(proc.) = 25 µmol/L
Written expression The threshold substance concentration of Arachidonate inducing aggregation by Thrombocytes in Mr. Smith’s Blood is [25] µmol/L. The measurement is performed by a procedure defined by the laboratory.
Equation

Reference

 NPU database, https://www.ifcc.org/ifcc-scientific-division/sd-committees/c-npu/npusearch/ and http://www.labterm.dk/default.aspx

  • Kind-of-property

    • Nominal kind-of-property

    • Kind-of-quantity

      • Unitary kind-of-quantity

        • Rational unitary kind-of-quantity

          • Threshold substance concentration

Reference
  • Dybkaer R. Concept system on ‘quantity’: formation and terminology. Accredit Qual Assur. 2013;18(3):253-60.
  • Dybkaer R. ISO terminological analysis of the VIM3 concepts ‘quantity’ and ‘kind-of-quantity’. Metrologia. 2010;47(3):127-34.
Date Term Note
1996-01-01 Threshold substance concentration Term established

NPU term identifier

 QU50006